The Agilent 1290 Infinity II LC is an ultra high pressure liquid chromatograph (UHPLC) connected to an Agilent 6135 single quadrupole using an electrospray ionization (ESI) source. This instrument offers high sample throughput using dual 1290 UHPLC pumps and full spectrum UV-VIS detection with a diode array detector.
UHPLC Specifications:
- Dual G7120A pumps (1300 bar max)
- G7167B injector with dual sampling loops and needles and G7116B 2-position heated column compartment for high throughput screening
- G7117B Diode Array Detector (UV-VIS, 190-640 nm, 240 Hz data rate)
LC MSD/XT Mass Spectrometer Specifications:
- 2-3000 m/z with fast scan rate (up to 10,000 amu/sec)
- Unit Mass Accuracy and Resolution: ±0.15 Da, 0.7 Da wide peaks
- Rapid polarity switching (<50 msec) enables positive and negative ion detection in a single analysis
- Jet Stream high sensitivity ESI source
Popular Assays:
- Organic reaction monitoring
- High throughput screening using nominal MS
- Quantitative LC/MS